Nakao Iwata Selected Research

Fluvoxamine (Luvox)

1/2014	Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients.
12/2013	Add-on fluvoxamine treatment for schizophrenia: an updated meta-analysis of randomized controlled trials.
6/2010	Duration of untreated illness and antidepressant fluvoxamine response in major depressive disorder.
1/2010	Genetic association analysis of functional polymorphisms in neuronal nitric oxide synthase 1 gene (NOS1) and mood disorders and fluvoxamine response in major depressive disorder in the Japanese population.
8/2009	Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population.
1/2009	Orphan nuclear receptor Rev-erb alpha gene (NR1D1) and fluvoxamine response in major depressive disorder in the Japanese population.
1/2009	CLOCK may predict the response to fluvoxamine treatment in Japanese major depressive disorder patients.
1/2006	Association study between vesicle-associated membrane protein 2 gene polymorphisms and fluvoxamine response in Japanese major depressive patients.

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Nakao Iwata Research Topics

Disease

166	Schizophrenia (Dementia Praecox) 11/2022 - 08/2004
47	Major Depressive Disorder (Major Depressive Disorders) 04/2022 - 01/2006
42	Bipolar Disorder (Manic Depressive Psychosis) 12/2021 - 09/2004
38	Psychotic Disorders (Schizoaffective Disorder) 01/2021 - 01/2005
14	Alzheimer Disease (Alzheimer's Disease) 10/2018 - 10/2014
13	Mental Disorders (Mental Disorder) 01/2022 - 09/2008
13	Sleepiness 12/2021 - 01/2013
11	Sleep Initiation and Maintenance Disorders (Insomnia) 12/2021 - 01/2009
11	Mood Disorders (Mood Disorder) 01/2021 - 07/2005
10	Dementia (Dementias) 01/2018 - 02/2009
9	Dizziness (Lightheadedness) 12/2021 - 02/2013
8	Psychomotor Agitation (Akathisia) 12/2021 - 02/2013
8	Weight Gain 12/2021 - 11/2013
8	Cognitive Dysfunction 04/2020 - 10/2008
7	Autism Spectrum Disorder 01/2022 - 01/2014
7	Nausea 12/2021 - 03/2008
7	Substance-Related Disorders (Drug Abuse) 01/2014 - 01/2005
6	Mania (Manias) 01/2022 - 07/2005
6	Body Weight (Weight, Body) 12/2020 - 03/2013
5	Agranulocytosis (Granulocytopenia) 01/2021 - 06/2013
5	Hyperprolactinemia 02/2019 - 02/2013
5	Headache (Headaches) 01/2019 - 06/2009
4	Anxiety Disorders (Anxiety Disorder) 12/2020 - 03/2008
4	Fatigue 01/2019 - 01/2015
3	Parkinson Disease (Parkinson's Disease) 01/2017 - 07/2015
3	Hallucinations (Hallucination) 01/2017 - 01/2013
3	Genetic Predisposition to Disease (Genetic Predisposition) 08/2015 - 08/2010
2	Treatment-Resistant Depressive Disorder 01/2022 - 04/2012
2	Depressive Disorder (Melancholia) 12/2021 - 01/2010
2	Constipation 12/2020 - 07/2017

Drug/Important Bio-Agent (IBA)

57	Antipsychotic Agents (Antipsychotics)IBA 01/2022 - 02/2005
35	Methamphetamine (Desoxyn)FDA LinkGeneric 08/2015 - 03/2005
19	Pharmaceutical PreparationsIBA 04/2022 - 03/2005
17	Aripiprazole (Abilify)FDA Link 11/2022 - 04/2010
14	Brain-Derived Neurotrophic Factor (BDNF)IBA 04/2022 - 09/2004
14	Serotonin (5 Hydroxytryptamine)IBA 01/2016 - 01/2003
13	blonanserinIBA 01/2022 - 02/2013
12	Memantine (Namenda)FDA Link 10/2018 - 09/2013
11	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2022 - 10/2008
10	Antidepressive Agents (Antidepressants)IBA 01/2021 - 01/2010
10	Glutamic Acid (Glutamate)FDA Link 10/2018 - 04/2007
10	Proteins (Proteins, Gene)FDA Link 08/2014 - 11/2004
9	Olanzapine (Zyprexa)FDA Link 01/2022 - 04/2010
9	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2018 - 03/2008
8	LithiumIBA 01/2022 - 04/2006
8	NucleotidesIBA 11/2020 - 12/2004
8	Fluvoxamine (Luvox)FDA LinkGeneric 01/2014 - 01/2006
7	Quetiapine Fumarate (Seroquel)FDA Link 01/2022 - 09/2013
6	Glutamate Receptors (Glutamate Receptor)IBA 01/2022 - 08/2004
6	Clozapine (Clozaril)FDA LinkGeneric 01/2021 - 06/2013
5	Paliperidone Palmitate FDA Link 01/2022 - 10/2013
5	Haloperidol (Haldol)FDA LinkGeneric 01/2022 - 02/2013
5	suvorexantIBA 12/2021 - 01/2015
5	Biological ProductsIBA 01/2021 - 04/2010
5	ProlactinIBA 12/2020 - 01/2016
5	N-Methylaspartate (NMDA)IBA 10/2018 - 08/2009
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2018 - 01/2008
5	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 08/2009 - 04/2008
4	Triglycerides (Triacylglycerol)IBA 08/2022 - 01/2014
4	Lurasidone Hydrochloride FDA Link 01/2022 - 01/2020
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 07/2005
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 07/2006
4	Dopamine (Intropin)FDA LinkGeneric 01/2019 - 06/2005
4	Cholinesterase Inhibitors (Anticholinesterases)IBA 10/2018 - 12/2014
4	Paroxetine (Paxil)FDA LinkGeneric 01/2017 - 03/2008
4	Messenger RNA (mRNA)IBA 08/2014 - 01/2008
4	5-HT1A Serotonin ReceptorIBA 03/2013 - 11/2009
4	serotonin 6 receptorIBA 01/2012 - 07/2010
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2011 - 01/2009
4	EnzymesIBA 03/2011 - 03/2005
3	C-Reactive ProteinIBA 08/2022 - 01/2016
3	HLA Antigens (Human Leukocyte Antigens)IBA 01/2021 - 04/2017
3	CholesterolIBA 12/2020 - 01/2014
3	brexpiprazoleIBA 05/2020 - 01/2018
3	CatecholaminesIBA 01/2019 - 09/2012
3	GABA-A Receptors (GABA(A) Receptor)IBA 05/2018 - 01/2005
3	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 04/2016 - 05/2009
3	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 01/2016 - 06/2009
3	Therapeutic UsesIBA 01/2016 - 08/2007
3	Mirtazapine (Rexer)FDA LinkGeneric 02/2014 - 09/2012
3	mosapramineIBA 01/2014 - 09/2013
3	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 03/2011 - 01/2009
3	DysbindinIBA 03/2010 - 11/2004
3	Neuregulin-1 (Neuregulin 1)IBA 08/2009 - 08/2004
2	Blood Glucose (Blood Sugar)IBA 08/2022 - 01/2014
2	HDL CholesterolIBA 08/2022 - 01/2019
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 04/2022 - 12/2020
2	Carbamazepine (Tegretol)FDA LinkGeneric 01/2022 - 01/2021
2	lemborexantIBA 12/2021 - 01/2020
2	OrexinsIBA 12/2021 - 08/2015
2	Cholinergic Antagonists (Anticholinergics)IBA 12/2021 - 09/2015
2	TabletsIBA 11/2021 - 01/2020
2	Lamotrigine (Lamictal)FDA LinkGeneric 01/2021 - 01/2019
2	Melatonin Receptors (Melatonin Receptor)IBA 01/2021 - 01/2019

Therapy/Procedure

24	Therapeutics 01/2022 - 07/2013
10	Injections 11/2021 - 01/2013
3	Transdermal Patch 01/2022 - 01/2020
3	Polypharmacy 02/2020 - 12/2014
2	Phototherapy (Light Therapy) 01/2021 - 01/2019
2	Drug Therapy (Chemotherapy) 02/2020 - 04/2013